Regioselective Synthesis of Fluorenones via the Consecutive In-Mediated Barbier Reaction, Pd-Catalyzed Cyclization, and Friedel-Crafts Reaction Starting from Baylis-Hillman Adducts
نویسندگان
چکیده
منابع مشابه
Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines.
Chiral squaramides are highly enantioselective catalysts for Friedel-Crafts reaction of indoles with N-tosyl imines, affording 3-indolyl methanamine products in 85-96% yields and 84-96% ees.
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The FeCl3·6H2O-catalyzed three-component aza-Friedel-Crafts reaction of aromatic/heteroaromatic compounds, aromatic aldehydes and tert-butyl carbamate was reported. The subsequent Friedel-Crafts-type alkylation of the resulting tert-butyl diarylmethyl carbamate with heteroaromatic compounds under "open-flask" at room temperature was also performed. The two-step reaction was especially useful fo...
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The kinetic data for a Baylis-Hillman reaction in certain ionic liquids possessing ethylsulfate anion [EtSO(4)](-) demonstrate that the rate determining step (RDS) is second order in aldehyde, but first order in acrylate and DABCO. This observation is similar to the one made by McQuade et al., who carried out this reaction in an aprotic polar solvent like DMSO. However, this is in contrast to t...
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ژورنال
عنوان ژورنال: Bulletin of the Korean Chemical Society
سال: 2011
ISSN: 0253-2964
DOI: 10.5012/bkcs.2011.32.4.1387